Colistin Sulfate Extraction
1. Feed Liquid Situation
Basic data | Feed | 14m³/hour |
Titer of colistin in fermentation broth | 600000-650000u/ml | |
Specific gravity | ~1.01 | |
Operating temperature | ≤50℃ | |
Technical indicators | Resin amount | 18m3 |
Water amount | ~13.5m3/hour | |
Titer of the system feed sulfa | ~160u/ml | |
Yield | ≥97% |
2. Extraction Process
After using the combination membrane system and fermentation softening system to pretreat the colistin fermentation broth, using the nature that colistin sulfate is high-value alkali compound, using the methyl acrylic acid-based resin or acrylic acid-based resin for ion exchange, and resolving withsulfuric acid, and finally getting the colistin sulfate.
3、Operating Cost
The total annual operating cost of equipment | 44 | 10,000 yuan |
Annual output | 3000 | ton/year |
Unit processing cost | 144.4 | yuan/ton |
unit consumption of electricity capacity | 58.2 | yuan/ton |
Amount of processing pure water unit consumption | 8.9 | yuan/ton |
Amount of unit acid consumption | 16.1 | yuan/ton |
Amount of unit alkali consumption | 55.2 | yuan/ton |
Amount of processing resin unit consumption | 4.3 | yuan/ton |
